Sensitivity and specificity of 6 stool-testing guidelines for identifying children with bacterial enteropathogens. Guidelines were applied to a cohort of children <18 years old with acute gastroenteritis (n = 2391) and were evaluated for their ability to recommend testing for children with bacterial enteropathogens (n = 144). Sensitivity and specificity were calculated separately for each multiply imputed dataset and were pooled, with their variances, using Rubin’s rules. Error bars indicate 95% confidence intervals (bars did not extend past the width of the point for the specificity of the CDC[12] and Klein et al [24]guidelines). The NICE[4] guidelines applied only to children <5 years old (n = 1977; bacterial enteropathogens n = 108). Physician discretion refers to laboratory tests ordered as part of routine care by the attending physician, separate from the study. Abbreviations: CDC, US Centers for Disease Control and Prevention; ESPGHAN, European Society for Pediatric Gastroenterology, Hepatology, and Nutrition; IDSA, Infectious Disease Society of America; NICE, National Institute for Health and Care Excellence.