Table 1.
Demographic and clinicopathologic characteristics (N=355)
| No. (%) or Median (IQR) | |
|---|---|
| Age at surgery, years | 63 (54–70) |
| Sex | |
| Female | 176 (50) |
| Male | 179 (50) |
| BMI (n=339) | 27.2 (23.7–30.5) |
| Smoking status | |
| Never | 52 (15) |
| Ever | 303 (85) |
| Pack-years (n=353) | 31.3 (15.0–50.0) |
| Tumor size on CT, cm (n=330) | 4.4 (3.0–6.0) |
| Primary tumor SUVmax (n=275) | 12.5 (8.0–17.2) |
| Preoperative histologic diagnosis (n=330) | |
| Adenocarcinoma | 119 (36) |
| Squamous cell carcinoma | 120 (36) |
| Other | 91 (28) |
| FEV1, % (n=353) | 82.0 (70.0–91.0) |
| DLCO, % (n=350) | 76.0 (63.0–90.0) |
| Induction therapy | |
| None | 181 (51) |
| Chemotherapy only | 151 (43) |
| Chemoradiotherapy | 23 (6.5) |
| ASA class | |
| I or II | 135 (38) |
| III or IV | 220 (62) |
| Total intravenous fluids, L | 1.2 (0.9–1.7) |
| Estimated blood loss, L | 0.6 (0.4–1.0) |
| Transfusion required in OR | |
| No | 298 (84) |
| Yes | 57 (16) |
| Surgery time, h | 3.4 (2.7–4.6) |
| Completion pneumonectomy | |
| No | 296 (83) |
| Yes | 59 (17) |
| Tumor location | |
| Left | 199 (56) |
| Right | 156 (44) |
| Final pathologic diagnosis | |
| Adenocarcinoma | 142 (40) |
| Squamous cell carcinoma | 134 (38) |
| Other | 68 (19) |
| No viable tumor | 11 (3.1) |
| Pathologic stage (AJCC 8th Edition) | |
| 0 | 11 (3.1) |
| I | 49 (14) |
| II | 119 (34) |
| III | 170 (48) |
| IV | 6 (1.7) |
| Extent of resection | |
| R0 | 333 (94) |
| R1 | 19 (5.4) |
| R2 | 3 (0.8) |
| Adjuvant therapy | |
| None | 140 (39) |
| Chemotherapy only | 110 (31) |
| PORT only | 75 (21) |
| Chemotherapy + PORT | 30 (8.5) |
AJCC, American Joint Committee on Cancer; ASA, American Society of Anesthesiologists; BMI, body mass index; CT, computed tomography; DLCO, diffusion capacity of the lungs for carbon monoxide; FEV1, forced expiratory volume in 1 second; OR, operating room; PORT, postoperative radiotherapy; SUVmax, maximum standardized uptake value.