Table 3.

Differentially expressed genes with persistent changes for H3K27Ac histone mark.

	2-wk Islets			10-wk Islets
Genes	RNAseq logFC	RNAseq FDR	H3K27Ac logFC	RNAseq logFC	RNAseq FDR	H3K27Ac logFC
Bcat2	−1.08	1.30 × 10−2	−0.98	−1.37	1.74 × 10−4	−0.88
Bhlha15	−2.12	8.77 × 10−5	−0.66	−1.42	5.75 × 10−3	−0.48
Cyp2t1	−0.99	1.14 × 10−2	−0.63	−0.78	3.54 × 10−2	−0.56
Dram1	−1.42	1.41 × 10−3	−0.12	−1.92	5.29 × 10−7	−0.76
Foxa3	−0.98	3.16 × 10−2	−0.67	−0.92	2.37 × 10−2	−0.47
Gpt2	−1.39	2.83 × 10−4	−0.59	−0.91	1.67 × 10−2	−0.77
Mast3	−1.10	2.69 × 10−4	−0.56	−0.83	4.53 × 10−3	−0.77
Ppard	−1.36	5.15 × 10−5	−0.06	−1.97	7.32 × 10−11	−0.74
Pycr1	−1.85	1.82 × 10−4	−0.87	−1.18	2.05 × 10−2	−0.82
Reep5	−0.92	4.49 × 10−2	−0.41	−1.48	2.62 × 10−5	−0.47
Tex49	−2.10	3.54 × 10−3	−0.33	−1.93	2.48 × 10−2	−1.35
Rnh1	−1.15	1.39 × 10−2	−0.28	−1.97	1.32 × 10−7	−0.56
Rnpepl1	−1.03	1.17 × 10−3	−0.64	−1.37	9.37 × 10−7	−0.48
Sel1l	−1.61	3.84 × 10−3	−0.38	−1.86	9.29 × 10−5	−0.95
Sfxn2	−1.42	2.34 × 10−3	−0.51	−0.97	3.91 × 10−2	−0.90
Tnip2	−0.61	3.89 × 10−2	−0.55	−0.59	2.96 × 10−2	−0.59
Tst	−1.26	1.41 × 10−2	−0.14	−3.13	9.28 × 10−14	−0.54
Ulk1	−1.03	2.87 × 10−5	−0.41	−0.70	4.26 × 10−3	−0.66
Wdtc1	−0.92	2.98 × 10−3	−1.01	−0.90	1.26 × 10−3	−0.51
Xbp1	−1.14	1.64 × 10−2	−0.56	−1.16	4.90 × 10−3	−0.84