Table 1.
Demographic and clinical characteristics of (ILA) and Ctrl from the validation cohort.
| Characteristics | Ctrl (n = 88) |
ILA (n = 57) |
p-Value |
|---|---|---|---|
| Gender, male (%) | 21 (24) | 25 (44) | 0.01 |
| Age, yr, mean (SD) | 65 (5) | 73 (8) | <0.0001 |
| BMI, kg/m2, mean (SD) | 27 (5) | 26 (4) | 0.13 |
| Former smoker, (%) | 42 (48) | 27 (47) | 0.5 |
| Diabetes mellitus, (%) | 20 (23) | 23(40) | 0.02 |
| Hypertension, (%) | 29(33) | 11(19) | 0.08 |
| Gastroesophageal reflux, (%) | 39 (44) | 22(39) | 0.6 |
| Meters W6MT, mean (SD) | 450 (101) | 408 (154) | 0.04 |
| spO2 at rest, mean (SD) | 95 (2) | 94 (2) | 0.03 |
| spO2 post exercise, mean (SD) | 92 (5) | 88 (9) | 0.0004 |
| DLCO adjusted (% predicted) mean (SD) | 104 (20) | 88 (19) | <0.0001 |
| DLCO/VA, mean (SD) | 6 (2) | 5 (1) | 0.001 |
Yr, year; BMI, body mass index; spO2, oxygen saturation; DLCO, diffusion capacity of the lung for carbon monoxide; VA, alveolar; SD, standard deviation. W6MT walking 6 min test. ILA, subjects with interstitial lung abnormalities; Ctrl, control group.