Table 4.
Half maximal inhibitory concentration of potential TcDHFR-TS inhibitors against T. cruzi and HFF1.
| Compound | IC50 μM T. cruzi |
IC50 μM HFF1 |
|---|---|---|
| NIL | 6 ± 2 | 12 ± 6 |
| GPZ | 13.4 ± 6 | 38 ± 11 |
| GLQ | 12 ± 5 | 68 ± 14 |
| GBD | 66 ± 12 | >50 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.