Table 1.

Ten significant keywords with q-value < 0.05 in each pathway cluster.

Cluster	Keywords
I	insulin, NGF, focal adhesion, BDNF, neurotrophins, Trk tyrosine kinase receptor, insulin receptor substrate, insulin receptor tyrosine kinase, Ras MAPK pathway, FAK
II	neuron
III	transcription, nucleoplasm, chromosome, nuclear content, nucleolus, RNA
IV	metabolism, mRNA, ribosome, replication, chemical reaction, cRNA, vRNA, viral protein, NUMB, nucleus
V	cell death, apoptotic process, activation, endogenous cellular process, programmed cell death, apoptosis
VI	mitochondrion, organelle, mitochondrial envelope, organelle envelope, lipid bilayer, inner elumen facing lipid bilayer, semiautonomous self replicating organelle, tissue respiration, virtually eukaryotic cell, cytoplasm
VII	degradation, APC/C, apoptosis, CDC20, CDH1, mitotic protein, MHC, multiubiquitination, ubiquitin 26s proteasome system, exogenous antigen
VIII	respiratory electron transport, ATP synthesis, inner mitochondrial membrane, chemiosmotic gradient, brown fat, rotenone, FAD, mitochondrial matrix, body temperature, NAD

Abbreviation. NGF: Nerve growth factor, BDNF: Brain-derived neurotrophic factor, MAPK: Mitogen-activated protein kinase, FAK: Focal adhesion kinase, RNA: Ribonucleic acid, APC/C: Anaphase-promoting complex, MHC: Major histocompatibility complex, ATP: Adenosine triphosphate, FAD: Flavin adenine dinucleotide, NAD: Nicotinamide adenine dinucleotide, NUMB, CDC20, CDH1: Gene names.