CRC |
Colorectal cancer |
CSCs |
Cancer stem cells |
5-FU |
5-Fluorouracil |
MiRNA |
MicroRNAs |
CD133 |
Cluster of differentiation 133 |
CD44 |
Cluster of differentiation 44 |
CD24 |
Cluster of differentiation 24 |
CD166 |
Cluster of differentiation 44 |
ESA |
Epithelial surface antigen |
Lgr5 |
Leucine-rich repeat-containing G-protein coupled receptor 5 |
APC |
Adenomatous polyposis coli |
TCF |
T-cell factor |
YAP1 |
Yes-associated protein 1 |
EMT |
Epithelial mesenchymal transition |
RTKs |
Receptor Tyrosine Kinases |
TEAD1 |
TEA domain family member 1 |
CYR61 |
Cysteine-rich angiogenic inducer 61 |
ANKRD1 |
Ankyrin Repeat Domain 1 |
MACC1
|
Metastasis-associated colon cancer 1
|
DSBs |
Double-strand breaks |
DDR |
DNA damage response |
ERCC1 |
Excision repair cross-complementing group 1 |
ROS |
Reactive oxygen species |
CCND1
|
Cyclin D1
|
TLE4 |
Transducinlike enhancer of Split |
PDCD4 |
Programmed Cell Death Protein 4 |
MTX |
Methotrexate |
FACS |
Fluorescence-activated cell sorting |
MMP6 |
Matrix metallopeptidase 16 |
HMGA1 |
high-mobility group A1 |
SFE |
Sphere-forming efficiency |
PKM1 |
Pyruvate kinase M1 |
PKM2 |
Pyruvate kinase M2 |
SIRT1 |
Sirtuin-1 |
PGC1α |
Peroxisome proliferator-activated receptor γ coactivator 1α |
RA |
Retinoic acid |
RAR |
Retinoic acid receptor |
STAT3 |
Signal transducer and activator of transcription 3 |
Chk2 |
Check point kinase 2 |
FOXM1 |
Forkhead box M1 |
AMPK |
AMP-activated protein kinase |