Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 26;9(6):1327. doi: 10.3390/cells9061327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Renin–angiotensin system (RAS) overexpression differentially regulates genes related to inflammation and cell stress in mice epididymal white adipose tissue (WAT). (A,B) RAS overexpression induces mitogen-activated protein kinase kinase kinase 7 (Map3k7) and mitogen activated protein kinase 14 (Mapk14/p38) expression compared to wild type (Wt) mice. (C) However, RAS overexpression significantly downregulated mitogen activated protein kinase kinase 3 (Map2k3) expression in Agt Tg compared to Wt mice. (D,E) Similar to Map3k7, histone deacetylase 4 (Hdac4) and activating transcription factor 6 (Atf6) were upregulated in Agt Tg group compared wild-type (Wt) mice WAT. Data are presented as mean ± SEM (n = 8). (** p < 0.001, * p < 0.05, # p < 0.1).