Table 2.

Genes predicted to be linked to ALS by the model trained on the manually curated list. For each gene, we reported the Ensembl gene name, coordinates (hg19) of the longest transcript, strand, and whether the gene was present in the other lists of genes or among their model predictions. Please note that if a gene were present in one list, it could not be predicted by its corresponding model.

	Ensembl Gene Name	Ensembl Transcript Name	Chr	Transcript Start	Transcript End	Strand	ClinVar Genes	ClinVar Predictions	DisGeNet Genes	DisGeNet Predictions	ALSoD Genes	ALSoD Predictions
ALS2	ENSG00000003393	ENST00000489440	2	202581364	202591275	−	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
BCL2L1	ENSG00000171552	ENST00000307677	20	30252254	30310701	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
BSG	ENSG00000172270	ENST00000573216	19	572571	581376	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
CASP1	ENSG00000137752	ENST00000436863	11	104896234	104905977	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
CHMP2B	ENSG00000083937	ENST00000466696	3	87302198	87303063	+	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
CLU	ENSG00000120885	ENST00000522413	8	27463898	27472209	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
CNTF	ENSG00000242689	ENST00000361987	11	58390145	58393198	+	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
CREBBP	ENSG00000005339	ENST00000574740	16	3786508	3794958	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
CST3	ENSG00000101439	ENST00000398409	20	23614293	23619110	−	FALSE	TRUE	TRUE	FALSE	TRUE	FALSE
CTSD	ENSG00000117984	ENST00000438213	11	1775253	1782770	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
DPP6	ENSG00000130226	ENST00000377770	7	153749764	154685161	+	FALSE	TRUE	TRUE	FALSE	TRUE	FALSE
ERBB4	ENSG00000178568	ENST00000484594	2	212426486	213403306	−	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
FOS	ENSG00000170345	ENST00000556324	14	75745530	75746234	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
GDI1	ENSG00000203879	ENST00000465640	X	153670112	153671075	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
GFAP	ENSG00000131095	ENST00000253408	17	42982993	42992920	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
GLE1	ENSG00000119392	ENST00000309971	9	131266978	131304567	+	FALSE	TRUE	TRUE	FALSE	TRUE	FALSE
GSR	ENSG00000104687	ENST00000221130	8	30535582	30585443	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
GSTP1	ENSG00000084207	ENST00000489040	11	67351604	67352535	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
GSX2	ENSG00000180613	ENST00000326902	4	54966197	54968672	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
HSF1	ENSG00000185122	ENST00000529630	8	145532954	145533780	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
INA	ENSG00000148798	ENST00000369849	10	105036919	105050108	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
JAK3	ENSG00000105639	ENST00000526008	19	17949078	17958841	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
JUND	ENSG00000130522	ENST00000600972	19	18390828	18391739	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
KIF3C	ENSG00000084731	ENST00000455394	2	26149470	26205366	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
LAT	ENSG00000213658	ENST00000566415	16	29000897	29001776	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
LDLR	ENSG00000130164	ENST00000560467	19	11215982	11224300	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
PARK7	ENSG00000116288	ENST00000465354	1	8021807	8031581	+	TRUE	FALSE	TRUE	FALSE	FALSE	FALSE
PLA2G4A	ENSG00000116711	ENST00000466600	1	186823417	186908362	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
PPARGC1A	ENSG00000109819	ENST00000264867	4	23793643	23891700	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
PRPH	ENSG00000135406	ENST00000551194	12	49687034	49687780	+	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
RXRA	ENSG00000186350	ENST00000484822	9	137208943	137298240	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
SELPLG	ENSG00000110876	ENST00000228463	12	109016604	109025854	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
SHC1	ENSG00000160691	ENST00000448116	1	154934773	154943223	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
SLC1A2	ENSG00000110436	ENST00000531628	11	35287147	35323075	−	FALSE	TRUE	TRUE	FALSE	TRUE	FALSE
SNAI1	ENSG00000124216	ENST00000244050	20	48599535	48605423	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
SOD2	ENSG00000112096	ENST00000541573	6	160103513	160113110	−	FALSE	TRUE	TRUE	FALSE	TRUE	FALSE
TIAM1	ENSG00000156299	ENST00000455508	21	32638611	32716594	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
TLE3	ENSG00000140332	ENST00000557815	15	70341315	70351129	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
TMSB4X	ENSG00000205542	ENST00000451311	X	12993226	12995346	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
TNF	ENSG00000232810	ENST00000449264	6	31543344	31546113	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
TP53	ENSG00000141510	ENST00000574684	17	7577571	7578437	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
TRPM7	ENSG00000092439	ENST00000558444	15	50867155	50874661	−	TRUE	FALSE	TRUE	FALSE	TRUE	FALSE
VIM	ENSG00000026025	ENST00000544301	10	17270257	17279584	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
WNT7A	ENSG00000154764	ENST00000285018	3	13857754	13921618	−	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE
XIAP	ENSG00000101966	ENST00000496602	X	123046609	123047465	+	FALSE	TRUE	TRUE	FALSE	FALSE	TRUE