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. 2020 Jun 25;11(6):704. doi: 10.3390/genes11060704

Table 1.

The classification of CRISPR/Cas systems.

Effector Module Pre-crRNA Processing Interference Stage (Target Cleavage)
Class 1 Type I Multi-subunit effector complex Cas6 Cas3
Type III Subunit of the processing complex
Type IV Uncharacterized
Class 2 Type II Single multi-domain protein RNase III Nuclease domain of the effector protein
Type V Nuclease domain of the effector protein
Type VI