APC	antigen presenting cell
BBB	Blood–brain barrier
BSCB	Blood–spinal cord barrier
CNS	central nervous system
CSF	cerebrospinal fluid
CXCL	C-X-C chemokine ligand
CXCR	C-X-C chemokine receptor
DC	dendritic cell
DMT	disease-modifying treatment/therapy
EAE	experimental autoimmune encephalomyelitis
ELR	glutamic acid-leucine-arginine motif
G-CSF	granulocyte-colony stimulating factor
GM-CSF	granulocyte-macrophage colony-stimulating factor
GPCR	G-protein-coupled receptor
HLA-DR	human leukocyte antigen – DR isotype
IgG	immunoglobulin G
IL	interleukin
IFN	interferon
LN	lymph node
MBP	myelin basic protein
MDM	monocyte-derived macrophage
MHC	major histocompatibility complex
MMP	matrix metalloproteinase
MOG	myelin oligodendrocyte glycoprotein
MPO	Myeloperoxidase
MRI	magnetic resonance imaging
MS	multiple sclerosis
NE	neutrophil elastase
NET	neutrophil extracellular trap
PAD	protein arginine deiminase
PLP	proteolipid protein
PPMS	primary progressive multiple sclerosis
REGA	remnant epitope generates autoimmunity
ROS	reactive oxygen species
RRMS	relapsing-remitting multiple sclerosis
SPMS	secondary progressive multiple sclerosis
TIMP	tissue inhibitor of metalloproteinase
TNF	tumor necrosis factor