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. 2020 Jun 26;9(6):1560. doi: 10.3390/cells9061560

Figure 2.

Figure 2

AbnobaViscum rapidly stimulate the release of cytotoxic granules and the production of IFNγ and TNFα in Vγ9Vδ2 T cells. (A–C) CD107a (A), IFN-γ (B) and TNF-α (C) expression on Vγ9+ T cells and Vγ9− T cells after AbnobaViscum Pini (Abnoba P) stimulation. Lines connect the same subjects (n = 6), bars indicate mean value. Values on the graphs indicate p values (obtained with the Wilcoxon signed-rank test). (D) Representative flow cytometry plots (4 h stimulation): the first two plots are gated on T cells (medium control on the left, Abnoba P on the right), the third plot is gated on Vγ9+ T cells (Abnoba P), illustrating CD107a, IFNγ and TNFα co-expression (E) Kinetics of CD107a expression on Vγ9+ T cells by Abnoba P, HMBPP, zoledronate and sec-butylamine (SBA). Lines connect the same subjects (n = 5), bars indicate mean values. Values on the graphs indicate p values (obtained with the paired T-test).