Figure 7.

Reduced alternatively activated M2 macrophage numbers in total lung of AdOSM-treated RELMα^–/– mice. (A) Enumeration of eosinophils, lymphocytes, macrophages and neutrophils recovered from BAL fluid. (B) Gating strategy (left panel) of F4/80⁺ macrophages and total CD38⁺ M1 or CD206⁺ M2 macrophages (right panel). (C) Gating strategy (left panel) and total IFNγ-producing CD4⁺ T cells. Data are represented as mean ± SEM (n = 5 mice/group). Statistical significance was determined by two-way ANOVA with Tukey’s post hoc test (^* p < 0.05, ^** p < 0.01, ^*** p < 0.001, ^**** p < 0.0001 between indicated groups).