Table 1.
Nongenetic Comparisons Between Age of Multiple Sclerosis (MS) Onset Groups.
| Characteristics | EOMS | AOMS | Sig 1 |
|---|---|---|---|
| Females | 19/28 (67.9%) | 43/72 (59.7%) | 0.499 |
| Age (years old) | 29.9 ± 9.8 | 39.8 ± 10.8 | 0.001 * |
| Duration of MS (months) | 148.1 ± 105.4 | 81.3 ± 69.1 | 0.011 * |
| EDSS | 3.1 ± 1.7 | 3.3 ± 1.6 | 0.414 |
| Primary Progressive | 3/28 (10.7%) | 7/72 (9.7%) | 0.917 |
| Relapses since onset | 5.2 ± 6.1 | 3.7 ± 2.5 | 0.393 |
| IgG index 2 | 1.3 ± 0.7 | 0.8 ± 0.4 | 0.004 * |
| Presence of OCBs 2 | 13/15 (86.7%) | 31/45 (68.9%) | 0.312 |
| Subcortical lesions 2 | 12/17 (70.6%) | 27/43 (62.8%) | 0.765 |
| Periventricular lesions 2 | 16/17 (94.1%) | 42/43 (97.7%) | 0.49 |
| Infratentorial lesions 2 | 12/17 (70.6%) | 30/43 (69.8%) | 1.000 |
| Spinal cord lesions 2 | 12/14 (85.7%) | 29/31 (93.5%) | 0.578 |
Numbers represent means ± standard deviation and absolute (%) frequencies; 1 Fisher exact test for categorical and Mann-Whitney U test for numerical characteristics. OCBs: Oligoclonal Bands, Sig.: significance. 2 Valid MRI and cerebrospinal fluid assessments were available for 60 (66%) and 60 (60%) patients, respectively. * p ≤ 0.05.