Figure 4.
Role of the SpTORC2 complex in transcriptional and epigenetic regulation. Dashed arrows indicate regulation that is either indirect, or not yet known to be direct. Solid lines indicate direct regulation. P denotes phosphorylation. The P circled with a dashed line indicates uncertainty about in vivo phosphorylation. Yellow circles indicate proteins that physically interact with Gad8. Notably, Paf1, Leo1, Taf12, and Pab1 are found primarily in the nucleus.