Table 2.
SF36 domains (norm-based scales) and PSQI global score at baseline and final follow-up (12 months), based on intention-to-treat analysis.
| SF36 domains | Baseline | Follow-up | Adj. difference (95% CI)§ | p § | ||
|---|---|---|---|---|---|---|
| CPAP (n = 55) | MAS (n = 49) | CPAP (n = 55) | MAS (n = 49) | |||
| Physical functioning | 48.2 (8.9) | 47.5 (8.2) | 50.0 (8.4) | 48.2 (9.6) | −1.6 (−4.4–1.1) | 0.23 |
| Role-physical | 49.6 (6.8) | 48.6 (8.3) | 51.4∗ (6.3) | 49.7 (8.2) | −1.9 (−4.4–0.5) | 0.13 |
| Bodily pain | 49.2 (11.4) | 46.3 (10.1) | 50.0 (10.7) | 46.8 (11.4) | −1.0 (−4.5–2.5) | 0.59 |
| General health | 45.4 (9.8) | 45.8 (10.6) | 48.2 (9.9) | 46.9 (10.7) | −1.1 (−4.1–2.0) | 0.48 |
| Vitality | 42.8 (11.4) | 39.8 (10.1) | 47.4∗ (10.8) | 47.7∗ (10.5) | 2.0 (−1.9–5.9) | 0.32 |
| Social functioning | 44.5 (12.4) | 42.2 (12.2) | 47.5 (12.4) | 46.5∗ (10.2) | 0.3 (−4.1–4.6) | 0.91 |
| Role-emotional | 48.4 (8.1) | 48.4 (8.1) | 49.5 (8.6) | 49.6 (7.4) | 0.2 (−2.7–3.0) | 0.91 |
| Mental health | 47.7 (10.0) | 47.8 (11.4) | 48.9 (11.7) | 50.4 (8.5) | 1.9 (−1.8–5.7) | 0.30 |
| Physical component score | 48.8 (7.6) | 47.0 (9.4) | 50.5∗ (8.0) | 47.5 (10.4) | −1.8 (−4.1–0.5) | 0.13 |
| Mental component score | 45.6 (10.3) | 44.9 (12.1) | 47.8 (12.3) | 49.3∗ (9.2) | 2.5 (−1.3–6.3) | 0.20 |
| PSQI global score | 7.7 (3.5) | 8.0 (3.1) | 6.6∗ (2.9) | 6.0∗ (2.6) | −0.8 (−1.8–0.1) | 0.09 |
CPAP: continuous positive airway pressure; MAS: mandibular advancement splint; PSQI: Pittsburgh Sleep Quality Index; SF36: Medical Outcomes Study Short-Form 36-Element Health Survey; SF36 domains and PSQI global score: mean (standard deviation). ∗Statistically significant change from baseline to follow-up within treatment group, paired t-test (p < 0.05). §Difference between MAS and CPAP treatment groups at follow-up, based on linear regression analysis adjusted for baseline variables (age, BMI, sex, smoking, baseline AHI, and the baseline SF36 domain/PSQI global score), reference group: CPAP.