Table 3.
SF36 domains (norm-based scales) and PSQI global score at baseline and final follow-up (12 months), based on per-protocol analysis (compliant patients only).
| SF36 domains | Baseline | Follow-up | Adj. difference (95% CI)§ | p § | ||
|---|---|---|---|---|---|---|
| CPAP (n = 18) | MAS (n = 36) | CPAP (n = 18) | MAS (n = 36) | |||
| Physical functioning | 47.9 (9.0) | 48.3 (7.7) | 49.8 (8.3) | 49.7 (9.1) | −0.8 (−4.5–2.8) | 0.64 |
| Role-physical | 49.4 (6.3) | 48.4 (9.0) | 50.4 (7.2) | 50.2 (8.3) | −0.3 (−4.1–3.6) | 0.89 |
| Bodily pain | 48.4 (12.4) | 46.7 (10.3) | 47.7 (11.7) | 46.9 (11.5) | 0.1 (−5.8–6.0) | 0.97 |
| General health | 45.9 (10.2) | 46.9 (10.5) | 49.1 (10.5) | 49.2 (10.1) | −0.4 (−4.9–4.2) | 0.88 |
| Vitality | 43.2 (13.7) | 39.8 (10.1) | 51.0∗ (9.4) | 50.2∗ (8.4) | 0.0 (−5.3–5.2) | 0.99 |
| Social functioning | 46.6 (12.7) | 41.9 (13.0) | 51.8∗ (8.7) | 47.7∗ (9.3) | −1.7 (−6.9–3.5) | 0.51 |
| Role-emotional | 49.5 (7.3) | 48.0 (8.8) | 51.3 (6.4) | 50.0 (7.4) | 0.3 (−3.6–4.1) | 0.89 |
| Mental health | 49.2 (8.8) | 47.2 (12.4) | 53.3 (8.1) | 51.5∗ (8.2) | −0.8 (−5.1–3.5) | 0.71 |
| Physical component score | 47.7 (8.3) | 47.9 (9.1) | 48.2 (8.7) | 48.5 (10.0) | 0.0 (−3.6–3.7) | 0.99 |
| Mental component score | 47.6 (9.6) | 44.1 (12.5) | 53.2∗ (4.9) | 50.5∗ (8.0) | −0.2 (−3.9–3.4) | 0.91 |
| PSQI global score | 7.1 (3.4) | 7.7 (3.3) | 5.7∗ (2.3) | 5.4∗ (2.5) | −0.6 (−1.7–0.5) | 0.25 |
CPAP: continuous positive airway pressure; MAS: mandibular advancement splint; PSQI: Pittsburgh Sleep Quality Index SF36: Medical Outcomes Study Short-Form 36-Element Health Survey; SF36 domains and PSQI global score: mean (standard deviation). ∗Statistically significant change from baseline to follow-up within treatment group, paired t-test (p < 0.05). §Difference between MAS and CPAP treatment groups at follow-up, based on linear regression analysis adjusted for baseline variables (age, BMI, sex, smoking, baseline AHI, and the baseline SF36 domain/PSQI global score), reference group: CPAP.