Skip to main content
. 2020 Jun 16;21(12):4271. doi: 10.3390/ijms21124271
AMD age-related macular degeneration
AMPK adenosine monophosphate-activated protein kinase
α-SMA alpha-smooth muscle actin
CEC choroidal endothelial cell
COL1A1 collagen type I alpha 1 chain
CNV choroidal neovascularization
CTGF connective tissue growth factor
EC endothelial cell
ECM extracellular matrix
EGF epidermal growth factor
EMT epithelial–mesenchymal transition
EndMT endothelial–mesenchymal transition
ENOS endothelial nitric oxide synthase
ERK extracellular-signal-regulated kinases
ERM epiretinal membrane
FAK focal adhesion kinase
FDG-PET fluorodeoxyglucose- positron emission tomography
FGF fibroblast growth factor
FN fibronectin
GA geographic atrophy
GFP green fluorescent protein
HGF hepatocyte growth factor
HUVECs human umbilical vein endothelial cells
ICAM intercellular adhesion molecule
IGF insulin-like growth factor
IL interleukin
LAP latency associated peptide
LTBP latent TGFβ-binding protein
MAPK mitogen-activated protein kinase
MMPs matrix metalloproteinase
MMT macrophage-myofibroblast transition
mtHsp70 mitochondrial heat shock protein
mTOR mammalian target of rapamycin
nAMD neovascular age-related macular degeneration
NRLP3 NLR Family Pyrin Domain Containing 3
PAI-1 plasminogen activator inhibitor type-1
PECAM-1 platelet-endothelial cell adhesion molecule-1
PET-MRI positron emission tomography-magnetic resonance imaging
PDGF platelet-derived growth factor
PDR proliferative diabetic retinopathy
PGC1α proliferator-activated receptor gamma coactivator 1-alpha
PI3K phosphatidylinositol-3 kinase
PVR proliferative vitreoretinopathy
OIR oxygen-induced retinopathy
OxLDL oxidized low density lipoprotein
Rho GTPase ras-homologous GTPase
ROP retinopathy of prematurity
ROS reactive oxygen species
RPE retinal pigment epithelium
RTK receptor tyrosine kinase
RUNX1 runt-related transcription factor 1
siRNA small interfering RNA
S1P sphingosine-1-phosphate
Taz transcriptional co-activator with PDZ-binding motif
TCF/LEF t-cell factor/lymphoid enhancer-binding factor
Tead transcriptional enhanced associate domains
TFs transcription factors
TGFβ transforming growth factor-β
TGFBR1 transforming growth factor-β receptor 1
TIE tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIMPs tissue inhibitors of matrix metalloproteinase
TNF-α tumor necrosis factor-α
TRPV4 transient receptor potential vanilloid 4
TSP1 thrombospondin 1
uPA urokinase-type plasminogen activator
uPAR urokinase-type plasminogen activator receptor
VCAM vascular cell adhesion molecule
VE-Cadherin vascular endothelial-cadherin
VEGF vascular endothelial growth factor
vWF von Willebrand Factor
Wnt Wingless/Integrated
YAP Yes-associated protein
Zeb zinc finger E-box-binding homeobox
ZO-1 zonula occludens-1