Table 3.
Cassette comparison between Ovis aries and Bos taurus.
| TRG1 locus | Ovis aries 4q3.1 | Bos taurus 4q3.1 | ||||
| Cassettes names | IMGT gene names | Nb of alleles | CDR-IMGT lengths | IMGT gene names | Nb of alleles | CDR-IMGT lengths |
| TRGC5 | TRGV11-1 | 1 P | [8.6.4] | |||
| TRGV3-1 | 2 F | [8.7.4] | TRGV3-1 | 1 F, 1 (F) | [8.7.4] | |
| TRGV3-2 | 1 F | [8.7.5] | TRGV3-2 | 1 F, 1 (F) | [8.7.4] | |
| TRGV7 | 1 F | [8.6.6] | TRGV7-1 | 1 F, 1 (F) | [8.6.6] | |
| TRGV10-1 | 1P | [9.7.4] | TRGV10-1 | 1 F | [9.7.5] | |
| TRGV4 | 2 F | [8.4.5] | TRGV4-1 | 1 (F) | [8.4.x] | |
| TRGJ5-1 | 1 F | - | TRGJ5-1 | 1 F | - | |
| TRGJ5-2 | 1 P | - | ||||
| TRGJ5-3 | 1 F | - | ||||
| TRGC5 (EX2A) | 1 (F) | - | TRGC5 (EX2A) | 1 F, 2 (F) | - | |
| (TRGC7) | TRGV8-1 | 1 F, 1 F | [3.8.4] | TRGV8-3 | 1 F, (1 F) | [3.8.5] |
| TRGV8-4 | 1 F | [3.8.5] | ||||
| TGRV8-1 | 1 F | [3.8.5] | ||||
| TRGV8-2 | 1 F, (1 F) | [3.8.5] | ||||
| TRGV2-1 | 2 F, 1 (F) | [6.8.5] del81,82,83 |
TRGV2-1 | 1 F | [6.8.5] del81,82,83 |
|
| TRGC7 (EX2A,2C) | 1 P | - | ||||
| TRGC3 | TRGV9-1 | 1 F, 1 (F) | [6.8.4] | TRGV9-1 | 1 F | [6.8.5] |
| TRGV9-2 | 1 F | [6.8.5] | ||||
| TRGJ3-1 | 1 F | - | TRGJ3-1 | 1 F, 1 (F) | - | |
| TRGJ3-2 | 1 P | - | ||||
| TRGC3 (EX2A,2C) | 1 F, 1 (F) | - | TRGC3 (EX2A,2C) | 1 F, 1 (F) | - | |
| TRGC4 | TRGV1 (L41) | 2 F | [5.8.5] | TRGV1-1 (L41) | 1 F, 2 (F) | [5.8.5] |
| TRGJ4-1 | 1 P | - | TRGJ4-1 | 1 F | - | |
| TRGJ4-2 | 1 F | - | TRGJ4-2 | 1 F | - | |
| TRGC4 (EX2A,2B,2C) | 1 (F) | - | TRGC4 (EX2A) | 1 F, 1 (F) | - | |
| TRG2 locus | Ovis aries 4q2.1 | Bos taurus 4q1.5-2.2 | ||||
| Cassettes | IMGT gene names | Nb of alleles | CDR-IMGT | Bos taurus | Nb of alleles | CDR-IMGT |
| TRGC1 | TRGV5-1 (L41) | 2 F | [5.8.5] del5-8 |
TRGV5-1 (L41) | 1 F, 4 (F) | [5.8.5] del5-8 |
| TRGJ1-1 | 1 F | - | TRGJ1-1 | 1 F | - | |
| TRGJ1-2 | 1 F | - | TRGJ1-2 | 1 F, 2 (F) | - | |
| TRGC1 (EX2A) | 1 F | - |
TRGC1 (EX2A,2B,2C) |
1 F, 3 (F) | - | |
| TRGC2 | TRGV6-1 | 1 F, 1 (F) | [5.8.5] del16 |
|||
| TRGV5-2 | 2 F | [5.8.5] del5-8 |
TRGV5-2* | 10 (F) | [5.8.5] del5-8 |
|
| TRGJ2-1 | 1 F | - | TRGJ2-1* | 1 F, 2 (F) | - | |
| TRGJ2-2 | 1 F | - | TRGJ2-2 | 1 F, 2 (F) | - | |
| TRGC2 (EX2A,2B,2C) | 1 F, 1 (F) | - | TRGC2 (EX2A,2B,2C) | 1 F, 4 (F) | - | |
| TRGC6 | TRGV6-1 | 1 F, 1 (F) | [5.8.5] del16 |
TRGV6-2* | 1 F | [5.8.5] del16 |
| TRGJ6-1 | 1 F | - | TRGJ6-1* | 1 F | - | |
| TRGJ6-2 | 1 F | - | - | |||
| TRGC6 (EX2A,2B,2C) | - | TRGC6 (EX2A,2B,2C) | 1 F, 1 (F) | - | ||
Highlighted (in yellow) are sequence features found in both Ovis aries and Bos taurus TRG sequences (‘del’ followed by numbers indicate gap (unoccupied) positions according to the IMGT unique numbering for V-DOMAIN [58], ‘L41’ indicates that the CONSERVED-TRP 41 is replaced by a leucine (L) in the V-REGION. ‘EX2A’, ‘EX2A,2C’ and ‘EX2A,2B,2C’ indicate exon designation for TRGC gene with 1, 2 or 3 Exons 2, respectively.