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. 2020 May 28;11(6):593. doi: 10.3390/genes11060593

Figure 1.

Figure 1

p21 binds cyclin/CDKs and PCNA. Scheme depicting sites of p21 binding partners and detailed regions within PCNA binding region. Threonine (Aspartic acid (TD) at position 148–149 and basic residue (R) in position 155 constitute the degron that is underlined in the model and detailed below. NLS, nuclear localization signal.