Figure 3.

Characterization of LTL331_CR_Tumor as NEPC. (A) Representative images showing IHC staining of LTL331, LTL331R, and LTL331_CR_Tumor. H&E, epithelial tumor marker pan-CK, proliferation marker Ki67, NE marker CD56, AR, and AR signaling marker PSA were stained as indicated in the images. Scale bar, 100 μm. (B) AR and NE scores of LTL331_CR_Tumor. NE and AR scores were calculated using transcriptomic data from LTL331_CR_Tumor. The scores were also calculated for other independent PDX models and LTL331_CR_Cell. Sample types are differentially colored based on their histopathological classifications.