Figure 5.

Interactions of L1 and L1 iron complex with the iron transport protein transferrin. Cartoon image of iron mobilization by L1 from diferric transferrin, which usually occurs in iron loaded patients and when high L1 concentration is present in plasma. In a reverse reaction, iron from the L1 iron complex can be donated to apo-transferrin increasing transferrin iron saturation. The latter reaction occurs in non-iron loaded patients with normal transferrin saturation treated with L1.