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. 2020 Jun 16;21(12):4278. doi: 10.3390/ijms21124278

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of berberine administration to the diabetic rats on the level of advanced glycation end-products (AGEs) in the lenses. The results are presented as an arithmetical mean ± SEM. Statistical significance of the results was evaluated by ANOVA followed by Tukey’s HSD post-hoc test. The results were considered statistically significant if p < 0.05: *** p < 0.001—statistically significant difference in comparison with the NDM group; ^# p < 0.05—statistically significant difference between the DM + BRB and DM groups. NDM: non-diabetic control rats, DM: diabetic control rats, DM + BRB: diabetic rats treated with berberine at a dose of 50 mg/kg p.o. for four weeks.