Table 1.

Principal component analysis of biochemical parameters measured in the lenses.

Principal Component	NDM	DM	DM + BRB
PC 1	−1.21 ± 0.38	2.01 ± 0.36 ***	−0.80 ± 0.47 ###
PC 2	0.77 ± 0.46	−0.63 ± 0.37 *	−0.14 ± 0.32

The results are presented as an arithmetical mean of PCA scores ± SEM. The statistical significance of the results was evaluated by multivariate analysis of variance (MANOVA) followed by Tukey’s HSD post-hoc test. The results were considered statistically significant if p < 0.05: * p < 0.05; *** p < 0.001—statistically significant differences in comparison with the NDM group; ^### p < 0.001—statistically significant difference between the DN + BRB and DM groups. NDM: non-diabetic control rats; DM: diabetic control rats; DM + BRB: diabetic rats treated with berberine at a dose of 50 mg/kg for four weeks; PC 1: principal component 1; PC 2: principal component 2.