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. 2020 Jun 26;9(6):1564. doi: 10.3390/cells9061564
3-HAO 3-hydroxyanthranilate oxidase
3-HK 3-hydroxykynurenine
AHR aryl hydrocarbon receptor
AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
ANA anthralinic acid
APC antigen presenting cell
ATP adenosine triphosphate
BBB blood-brain barrier
CDxx cluster of differentiation xx
CHMP Committee for Medicinal Products for Human Use
CNS central nervous system
DC dendritic cell
EAE experimental autoimmune encephalitis
GRP35 G-protein coupled receptor 35
IDO 1,2 izoenzymes indoleamine 2,3-dioxygenase 1 and 2
IFN-β interferon beta
IFN-γ interferon gamma
IL interleukin
KAT 1, 2 kynurenine aminotransferase 1 and 2
KMO kynure nine 3-monooxygenase
KP kynurenine pathway
KYN kynurenine
KYNA kynurenic acid
MMP9 matrix metalloproteinase 9 (MMP9)
MP methoxyndole pathway
MS multiple sclerosis
NAD+ nicotinamide adenine dinucleotide
NADP+ nicotinamide adenine dinucleotide phosphate
NaMN nicotinic acid mononucleotide
NAS N-acetylserotonin
NK natural killer cell
NMAPT nicotinamide phosphoribosyltransferase
NMDA N-methyl-D-aspartate
NMDA N-methyl-D-aspartate receptor
NMN nicotinamide mononucleotide
NMNAT nicotinamide mononucleotide adenyl transferase
PARP poly(ADP-ribose) polymerase
PBMC peripherial blood monocytes
PMN polymorphonuclear cells
PPMS primary progressive multiple sclerosis
QUIN quinolinic acid
RRMS relapsing-remitting multiple sclerosis
SS Sjögren’s syndrome
TDO tryptophan 2,3-dioxygenase
TGF-β transforming growth factor beta
TNFα tumor necrosis factor alpha
Treg regulatory T cell
TRP tryptophan
VLA-4 very late antigen-4