3-HAO |
3-hydroxyanthranilate oxidase |
3-HK |
3-hydroxykynurenine |
AHR |
aryl hydrocarbon receptor |
AMPA |
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid |
ANA |
anthralinic acid |
APC |
antigen presenting cell |
ATP |
adenosine triphosphate |
BBB |
blood-brain barrier |
CDxx |
cluster of differentiation xx |
CHMP |
Committee for Medicinal Products for Human Use |
CNS |
central nervous system |
DC |
dendritic cell |
EAE |
experimental autoimmune encephalitis |
GRP35 |
G-protein coupled receptor 35 |
IDO 1,2 |
izoenzymes indoleamine 2,3-dioxygenase 1 and 2 |
IFN-β |
interferon beta |
IFN-γ |
interferon gamma |
IL |
interleukin |
KAT 1, 2 |
kynurenine aminotransferase 1 and 2 |
KMO |
kynure nine 3-monooxygenase |
KP |
kynurenine pathway |
KYN |
kynurenine |
KYNA |
kynurenic acid |
MMP9 |
matrix metalloproteinase 9 (MMP9) |
MP |
methoxyndole pathway |
MS |
multiple sclerosis |
NAD+
|
nicotinamide adenine dinucleotide |
NADP+
|
nicotinamide adenine dinucleotide phosphate |
NaMN |
nicotinic acid mononucleotide |
NAS |
N-acetylserotonin |
NK |
natural killer cell |
NMAPT |
nicotinamide phosphoribosyltransferase |
NMDA |
N-methyl-D-aspartate |
NMDA |
N-methyl-D-aspartate receptor |
NMN |
nicotinamide mononucleotide |
NMNAT |
nicotinamide mononucleotide adenyl transferase |
PARP |
poly(ADP-ribose) polymerase |
PBMC |
peripherial blood monocytes |
PMN |
polymorphonuclear cells |
PPMS |
primary progressive multiple sclerosis |
QUIN |
quinolinic acid |
RRMS |
relapsing-remitting multiple sclerosis |
SS |
Sjögren’s syndrome |
TDO |
tryptophan 2,3-dioxygenase |
TGF-β |
transforming growth factor beta |
TNFα |
tumor necrosis factor alpha |
Treg |
regulatory T cell |
TRP |
tryptophan |
VLA-4 |
very late antigen-4 |