Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed mechanism for regeneration in the adult proximal tubule. Upon injury, generic differentiated epithelial cells dedifferentiate, proliferate and redifferentiate to repair the damage. During this process, differentiated cells lose markers of differentiation (e.g., the brush border, specific transporters) and upregulate markers that indicate a stem or progenitor cell state (CD24, CD133, Vimentin and probably CD44, SOX9 and PAX2 as well).
