Figure 1.

Effective Parkin overexpression in skeletal muscles of Sham and CLP operated mice. (A) Initial body weight and (B) percent of body weight loss in Sham-operated and or CLP mice. (C) qPCR analysis of Park2 expression levels in the gastrocnemius muscles injected with either AAV-GFP or AAV-Parkin in Sham and CLP mice. (D) Representative Parkin immunoblots and its corresponding ponceau S stain performed on gastrocnemius samples of Sham and CLP mice injected with either AAV-GFP or AAV-Parkin. 1 = Sham-AAV-GFP; 2 = Sham-AAV-Parkin; 3 = CLP-AAV-GFP; 4 = CLP-AAV-Parkin. Data are presented as mean ± SEM (n = 7–9/group; * = statistically significant; ns = not statistically significant).