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. 2020 Jun 16;21(12):4283. doi: 10.3390/ijms21124283

Table 1.

Signalling pathways involved in the regulation of adipogenesis.

Signalling Pathways Effect on Adipocyte Differentiation References
IGF-1 Promotes [37,38,39,40]
Glucocorticoid Promotes [42,43,44,45]
cAMP Promotes [46,47,48,49,50]
TGF-β1 and 2 Inhibits [52,53,54,55]
BMP2 Promotes [59,60]
BMP4 Promotes [53,56,57,58]
BMP7 Promotes [55,61,62,63,64]
Wnt Inhibits [65,69,70,72]
Hedgehog Inhibits [74,76]
ERK/MAPK Promotes [78]
Inhibits [79,80]
P38/MAPK Promotes [81,82,83]
Inhibits [77]
Ras Promotes [37,84]
Retinoblastoma protein Inhibits [85]
Myostatin Inhibits [88]