Table 1.
Signalling Pathways | Effect on Adipocyte Differentiation | References |
---|---|---|
IGF-1 | Promotes | [37,38,39,40] |
Glucocorticoid | Promotes | [42,43,44,45] |
cAMP | Promotes | [46,47,48,49,50] |
TGF-β1 and 2 | Inhibits | [52,53,54,55] |
BMP2 | Promotes | [59,60] |
BMP4 | Promotes | [53,56,57,58] |
BMP7 | Promotes | [55,61,62,63,64] |
Wnt | Inhibits | [65,69,70,72] |
Hedgehog | Inhibits | [74,76] |
ERK/MAPK | Promotes | [78] |
Inhibits | [79,80] | |
P38/MAPK | Promotes | [81,82,83] |
Inhibits | [77] | |
Ras | Promotes | [37,84] |
Retinoblastoma protein | Inhibits | [85] |
Myostatin | Inhibits | [88] |