Table 3.
MicroRNAs involved in the regulation of adipogenesis.
| MicroRNAs | Target | Experimental Model | References |
|---|---|---|---|
| Proadipogenic | |||
| MiR-143 | ERK5 (MAPK signalling pathway) | Human preadipocytes | [135] |
| MiR 17-92 | RB2/P130 | 3T3-L1 cells | [138] |
| MiR-125b-5p | Smad 4 | 3T3-L1 cells | [139] |
| MiR 30 a and d | Runx2 | HASCs | [140] |
| MiR-204 and MiR-211 | Runx2 | C3H10T1/2 | [141] |
| MiR-124 | Dlx4 | 3T3-L1 cells | [136] |
| MiR-210 | Tcf712 (Wnt signalling pathway) | 3T3-L1 cells | [69] |
| MiR-146 | Sirt 1/FOXO1 | 3T3-L1 cells | [144] |
| Antiadipogenic | |||
| MiR-130 | PPARγ | 3T3-L1 cells | [142] |
| MiR-27a and b | PPARγ and C/EBPα | 3T3-L1 cells | [143] |
| MiR-93 | Sirt 7 and Tbx3 | miR-25-93-106b–/– mice | [145] |