Figure 2.
Age dependence of T2, fractional anisotropy, diffusivity, and kurtosis measures in the whole brain of male guinea pigs. Graphs illustrate the age dependence of T2 (A), fractional anisotropy (FA) (B), diffusivity measures (C), and kurtosis measures (D) in the guinea pig brain. Symbols and error bars represent mean and SD of results obtained from 6 guinea pigs examined longitudinally at postnatal day (PND) 18-25 (juvenile), PND 46-51 (adolescent), and PND 118-123 (adult). Whenever ANOVA revealed a significant effect of age on a given parameter, the Tukey post-hoc test was used for multi-group comparisons. Asterisks and daggers are used for comparison with data obtained at PND 18-25 and PND 46-51, respectively. *, p < 0.05, **, p < 0.01, ***, p < 0.001; †††, p < 0.001.