Table 1.
Proinflammatory agents analyzed via antibody array in conditioned media of untreated NAHAs.
| Cytokines | |||
|---|---|---|---|
| Name | Gene | UniProtKB ID | Expression |
| Interleukin-1α | IL1A | P01583 | nd |
| Interleukin-1β | IL1B | P01584 | + |
| Interleukin-2 | IL2 | P60568 | nd |
| Interleukin-3 | IL3 | P08700 | + |
| Interleukin-4 | IL4 | P05112 | nd |
| Interleukin-6 | IL6 | P05231 | + |
| Interleukin-7 | IL7 | P13232 | nd |
| Interleukin-10 | IL10 | P22301 | nd |
| Interleukin-11 | IL11 | P20809 | nd |
| Interleukin-12 subunit-α | IL12A | P29459 | nd |
| Interleukin-12 subunit-β | IL12B | P29460 | nd |
| Interleukin-13 | IL13 | P35225 | nd |
| Interleukin-15 | IL15 | P40933 | nd |
| Interleukin-16 | IL16 | Q14005 | + |
| Interleukin-17A | IL17 | Q16552 | nd |
| Interferon-γ | IFNG | P01579 | nd |
| Granulocyte colony-stimulating factor | CSF3 | P09919 | nd |
| Granulocyte-macrophage colony-stimulating factor | CSF2 | P04141 | nd |
| Lymphotoxin-α | TNFB | P01374 | nd |
| Macrophage colony-stimulating factor-1 | CSF1 | P09603 | nd |
| Transforming growth factor-β1 | TGFB1 | P01137 | nd |
| Tumor necrosis factor-α | TNFA | P01375 | nd |
| Cytokine Soluble Receptors | |||
| Interleukin-6 receptor subunit-α | IL6R | P08887 | nd |
| TNF receptor superfamily member-1α | TNFRSF1A | P19438 | nd |
| TNF receptor Superfamily Member-1β | TNFRSF1B | P20333 | nd |
| Chemokines | |||
| C-C motif chemokine-1 | CCL1 | P22362 | nd |
| C-C motif chemokine-5/RANTES | CCL5 | P13501 | + |
| C-X-C motif chemokine-9 | CXCL9 | Q07325 | nd |
| C-X-C motif chemokine-10 | CXCL10 | P02778 | nd |
| Eotaxin-1 | CCL11 | P51671 | nd |
| Eotaxin-2 | CCL24 | O00175 | nd |
| Interleukin-8 | CXCL8 | P10145 | + |
| Monocyte chemoattractant protein-1 | CCL2/MCP1 | P13500 | + |
| Monocyte chemoattractant protein-2 | CCL8/MCP2 | P80075 | + |
| Macrophage inflammatory protein-1α | CCL3 | P10147 | nd |
| Macrophage inflammatory protein-1β | CCL4 | P13236 | nd |
| Macrophage inflammatory protein-5 | CCL15 | Q16663 | nd |
| Other agents | |||
| Soluble intercellular adhesion molecule-1 (s-ICAM-1] | ICAM1 | P05362 | + |
| Metalloproteinase inhibitor-2 | TIMP2 | P16035 | + |
| Platelet-derived growth factor subunit-B | PDGFB | P01127 | + |
nd, not detected; +, detected.