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. 2020 May 31;9(6):1361. doi: 10.3390/cells9061361

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Structural details of RIP cleavages. (a) TACE (⍺1, ⍺2, orange) and BACE (β1, yellow) cleavage sites on EpEX shown in two different orientations. (b) γ-secretase (γ1–γ3 and ε1, ε2; light orange) cleavage sites in EpCAM transmembrane region.