Table 1.
Characteristics of pneumococcal conjugate vaccines (PCVs; PCV13, PCV10 A and PCV10 B).
| Characteristics | PCV13 | PCV10 A | PCV10 B | ||
|---|---|---|---|---|---|
| 1 Dose/Vial | 4 Dose/Vial | 4 Dose/Vial | 1 Dose/Vial | 5 Dose/Vial | |
| Serotypes | 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 23F | 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F | 1, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 23F | ||
| WHO Prequalification | 2010 | 2016 | 2017 | 2020 | 2020 |
| Price per dose | $3.30 */$20.83 ** | $2.90 * | $3.05 * | $3.50 * | $2.00 * |
| Doses per fully immunized child | 3 | 3 | 3 | 3 | 3 |
| Indicative wastage rate | 5% | 8% | 8% | 5% | 8% |
| Shelf-life | 36 months at 2–8 ℃ | 36 months at 2–8 ℃ | 36 months at 2–8 ℃ | 36 months at 2–8 ℃ | 36 months at 2–8 ℃ |
| Cold chain volume per dose *** | 12.6 cm³ | 3.9 cm³ | 2.7 cm³ | 17.0 cm³ | 3.7 cm³ |
| Cost of cold room (per cm³) **** | $0.0013 | $0.0013 | $0.0013 | $0.0013 | $0.0013 |
| Handling open vials | N.A. | Opened vials may be kept for use in subsequent immunization sessions (up to 28 days from the withdrawals of the first injection if held at 2 to 8 ℃) | Opened vials may be kept for use in subsequent immunization sessions (up to 28 days from the withdrawals of the first injection if held at 2 to 8 ℃) | N.A. | Opened vials may be kept for use in subsequent immunization sessions (up to 28 days from the withdrawals of the first injection if held at 2 to 8 ℃) |