Table 2.
Input parameters.
| Parameter | Value | Reference |
|---|---|---|
| Vaccine price | ||
| PCV13—1 dose/vial (Government contract price) | Base value = $20.83 (Min = $18.94; Max = $61.00) | [22] |
| PCV13—1 dose/vial (UNICEF price) * | Base value = $3.30 (Lower = $2.48; Upper = $4.13) | [61] |
| PCV13—4 doses/vial (UNICEF price) * | Base value = $2.90 (Lower = $2.18; Upper = $3.63) | [61] |
| PCV10 A—4 doses/vial (UNICEF price) * | Base value = $3.05 (Lower = $2.29; Upper = $3.81) | [61] |
| PCV10 B—5 doses/vial (UNICEF price) * | Base value = $2.00 (Lower = $1.50; Upper = $2.50) | [61] |
| Additional cost | ||
| Total additional cost ** | Base value = 23.0% (Min = 19.5%, Max = 38.0%) | |
| Vaccine wastage | ||
| Single-dose/vial | Median = 5.0% (Min = 1%; Max = 10%) | [26] |
| Multi-dose/vial | Median = 7.0% (Min = 1%; Max = 27%) | [26] |
| Safety stock | ||
| Total safety stock | Base value = 5% (Min = 0%; Max = 10%) | |
| Vaccine coverage | ||
| National coverage | Base value = 90.8% (Min = 46%, Max = 100%) | [25] |
| Cost of cold room | ||
| Cost per cm3 *** | Base value = $0.0013 (Min = $0.0005; Max = $0.0022) | [26,27] |
| IPD in children <1 years old | ||
| Incidence rate (per 100,000 population) | 2911 (Range = 2265–3622) | [62] |
| Risk reduction for IPD | ||
| PCV13 | Odds Ratio = 0.53 (95% CI; 0.36–0.78) | [30] |
| PCV10 A | Odds Ratio = 0.19 (95% CI; 0.11–0.33) | [30] |
| PCV10 B | N.A. |
N.A.: not applicable; * Lower and upper value: ± 25%; ** Base value (costs of forwarder, distribution, insurance and service fee), Min (costs of the forwarder, distribution and insurance) and Max (costs of tax, import duty, forwarder, distribution, insurance and service fee); *** Base value (cold room size: 10 m3), Min (cold room size: 40 m3) and Max (cold room size: 5 m3).