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. 2020 Jun 2;8(2):269. doi: 10.3390/vaccines8020269

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of monoclonal antibodies on H. capsulatum unsaturated fatty acid biosynthesis. (A,B) Abundance profiles of delta-9 fatty acid desaturase (A) and oleate delta-12 desaturase in H. capsulatum cells treated with monoclonal antibodies. (C) Enzymes and metabolites of the unsaturated fatty acid biosynthesis pathway. (D) Abundance profiles of free fatty acids (not bound to complex lipids) in H. capsulatum yeast cells treated with monoclonal antibodies. Abbreviations: CTL, control; UC, untreated control without hybridoma medium; t-test: NS, not significant. * p ≤ 0.05 compared to the control sample.