FIGURE 3.

Sequence mutations of the ten most retrieved PLMVd variants. The nucleotide sequence and secondary structure of PSTVd-RG1. The structural/functional domains of PSTVd: TL, P, C, V, and TR are delimited by the vertical solid lines and are named accordingly. The A-motif, Central Conserved Region (CCR), loop E, and RY-motif are indicated. Additionally, the sequence that form the metastable structure hairpin I (HPI) via pairing of distant complementary nucleotides sequences is enlarged. The arrows indicate the positions where mutations occurred. Nucleotide insertion, deletion and substitution are shown in black, red, and green, respectively.