Figure 6.

Expression of STING in the murine lung parenchyma (a,c,e), bronchi, and bronchioles (b,d,f). Formalin-fixed, paraffin-embedded lung sections from female C57BL/6J wild type (WT) mice and STING knockout mice at 10 weeks of age were stained with rabbit-anti-STING (c–f) or with isotype control rabbit IgG (a,b). Bound antibody was detected by AF647 conjugated-goat anti-rabbit IgG, and the images were captured on a Zeiss confocal microscope. STING expression (red) was seen in cells lining the alveoli (c) and in bronchial epithelium (d). Nuclei were stained with DAPI and appear blue. Scale bar = 50 μm.