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. 2020 Jun 25;21(12):4512. doi: 10.3390/ijms21124512

Figure 7.

Figure 7

STING expression in the hematopoietic cells is critical for the development of lung inflammation in DMXAA treated mice. Representative images of hematoxylin and eosin-stained lung sections from bone marrow chimeras one month after injection with vehicle (a,b) or DMXAA (c,d). Lung inflammation (arrows) was seen following DMXAA treatment in STING KO mice reconstituted with WT bone marrow. Scale bar = 50 μm. (e) Lung inflammation in vehicle and DMXAA treated chimeric mice one month after injection. Results are pooled from two independent experiments. Two-tailed, Mann–Whitney test was used to determine the statistical significance, and p < 0.05 was considered significant (●: Vehicle-treated, ○: DMXAA-treated).