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. 2020 Jun 24;21(12):4487. doi: 10.3390/ijms21124487

Figure 11.

Figure 11

The overlaps and differences of the ten genes shown in Figure 1, Figure 2, Figure 3, Figure 4, Figure 5, Figure 6, Figure 7, Figure 8, Figure 9 and Figure 10 showed that one gene was upregulated in normal testis (NT), and other genes were upregulated in germ cell neoplasia in situ (GCNIS). Undifferentiated histologic types, seminoma (SE) and embryonal carcinoma (EC), differed in RNA expression. EC differed in RNA expression from the differentiated histologic types such as choriocarcinoma (CC), yolk sac tumor (YST), and teratoma (TER). The figure indicates the linkage among the histologic types. The change from GNIS to SE was associated with a change in RNA expression of three significant genes. As for the genes, red arrows denote increased RNA expression and the blue arrows denote reduced RNA expression.