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. 2020 May 30;8(2):262. doi: 10.3390/vaccines8020262

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Detection of IL-10 and IFN-α in sera from pigs after immunisation and challenge. Panel (a) shows IFN-α and panel (c) IL-10 detected in serum at different days post-immunisation. The y-axis shows the amount detected in Units per ml, and the x-axis shows the days post-immunisation. The results for pigs immunised with OURT88/3 are shown in red (wt_1–5), with OURT88/3ΔI329L in blue (del_1–6) and control pigs in green (control_1–3). Panels (b,d) show the results post-challenge analysed to determine statistical differences between groups. Asterisks indicate statistically significant differences between groups (*** p ≤ 0.001; **** p ≤ 0.0001).