Skip to main content
. 2020 May 28;8(2):254. doi: 10.3390/vaccines8020254

Figure 1.

Figure 1

Construction of the immunopotent foot-and-mouth disease virus (FMDV) vaccine strains A-3A and A-HSP70. (A,B) represent: (A) A-3A; (B) A-HSP70. FMDV T cell epitope 3A (the 15 amino acid residues in VP1) (A) and enhanced long-term immunity protein HSP70 (the 20 amino acid residues of VP1) (B) were selected as target molecules for preparation of immunopotent virus. The A22 (A22-R) P1, where the P1 region of O1 Manisa is substituted with A22 P1, was used as the backbone for the preparation of immunopotent FMD vaccine strains. The detailed strategy is presented in the Materials and Methods.