Table 1.
List of apoptosis-related mRNAs regulated by hnRNP H1.
| IP-Transcriptome Analysis (hnRNP H1/IgG) | Transcriptome Analysis (siRNA of hnRNP H1/Scramble) | IP-Transcriptome Analysis (hnRNP H1/IgG) | Transcriptome Analysis (siRNA of hnRNP H1/Scramble) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Fold Change | p-Value | Fold Change | p-Value | Fold Change | p-Value | Fold Change | p-Value | ||
| ACVR2B | 15.144 | 0.0006 | −2.574 | 0.026 | PPP2R3A | 2.530 | 0.0060 | −2.047 | 0.0200 |
| AJUBA | 11.234 | 0.0004 | −2.678 | 0.039 | PPP2R5D | 2.298 | 0.0019 | −2.490 | 0.0442 |
| AMOTL2 | 2.834 | 0.0002 | −2.737 | 0.019 | PPP3CC | 2.502 | 0.0176 | −2.200 | 0.0350 |
| APAF1 | 10.245 | 0.0002 | −2.008 | 0.037 | PRKAG1 | 12.766 | 0.0000 | −3.006 | 0.0166 |
| ATF6 | 6.076 | 0.0014 | −2.254 | 0.044 | PTK2 | 2.441 | 0.0002 | −2.921 | 0.0063 |
| AXL | 2.068 | 0.0030 | −2.603 | 0.018 | RAP1A | 35.974 | 0.0001 | −2.280 | 0.0242 |
| CASP7 | 6.792 | 0.0007 | −4.722 | 0.001 | RARG | 3.885 | 0.0000 | −2.098 | 0.0291 |
| CLIP3 | 15.400 | 0.0225 | −2.544 | 0.020 | RASSF3 | 17.411 | 0.0002 | −2.738 | 0.0104 |
| CTGF | 4.658 | 0.0156 | −4.238 | 0.009 | RASSF6 | 4.301 | 0.0434 | −3.561 | 0.0023 |
| CYR61 | 28.917 | 0.0000 | −3.997 | 0.001 | RIT1 | 17.399 | 0.0005 | −2.506 | 0.0157 |
| EHHADH | 3.697 | 0.0000 | −2.225 | 0.004 | RPS6KB1 | 12.641 | 0.0001 | −2.086 | 0.0472 |
| EPHA2 | 3.509 | 0.0000 | −2.418 | 0.049 | SAV1 | 3.466 | 0.0036 | −2.038 | 0.0209 |
| ETS1 | 16.393 | 0.0000 | −3.354 | 0.003 | SENP2 | 9.278 | 0.0002 | −2.756 | 0.0078 |
| F3 | 5.165 | 0.0003 | −3.409 | 0.003 | SERPINE1 | 3.547 | 0.0016 | −4.902 | 0.0018 |
| HHAT | 6.855 | 0.0334 | −2.084 | 0.041 | SGPL1 | 4.066 | 0.0002 | −2.714 | 0.0106 |
| KAT2B | 20.055 | 0.0027 | −2.428 | 0.045 | SMPD1 | 2.1766 | 0.0011 | −3.8267 | 0.0158 |
| KCTD11 | 44.393 | 0.0009 | −3.208 | 0.025 | SMURF2 | 8.1538 | 0.0007 | −2.7949 | 0.0174 |
| M6PR | 3.165 | 0.0008 | −2.590 | 0.007 | SRF | 20.2462 | 0.0000 | −2.5036 | 0.0222 |
| MAP3K1 | 3.446 | 0.0061 | −2.085 | 0.027 | SSH2 | 4.7555 | 0.0001 | −2.7527 | 0.0168 |
| MAP3K14 | 2.762 | 0.0011 | −2.830 | 0.020 | SYN2 | 3.0399 | 0.0349 | −2.7661 | 0.0085 |
| MAP4K4 | 13.365 | 0.0001 | −2.783 | 0.015 | TBK1 | 4.9114 | 0.0003 | −2.6957 | 0.0153 |
| MAPKAPK2 | 3.004 | 0.0028 | −2.989 | 0.017 | TEAD4 | 14.2232 | 0.0001 | −2.3833 | 0.0489 |
| NRAS | 4.051 | 0.0043 | −3.585 | 0.002 | TRAF5 | 7.1550 | 0.0042 | −2.1078 | 0.0394 |
| NUMB | 2.974 | 0.0016 | −2.286 | 0.041 | UNC13D | 2.6362 | 0.0043 | −2.7414 | 0.0298 |
| PDLIM2 | 6.149 | 0.0002 | −2.971 | 0.034 | YAP1 | 31.9441 | 0.0002 | −2.9568 | 0.0125 |
| PLCG1 | 25.086 | 0.0000 | −2.500 | 0.031 | YES1 | 6.5590 | 0.0002 | −4.2868 | 0.0046 |
| PPM1F | 9.955 | 0.0000 | −2.442 | 0.035 | ZMYND15 | 7.6683 | 0.0002 | −2.8244 | 0.0094 |