Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In situ assessment of mRNA preservation quality in FFPE kidney biopsies. Immunofluorescent in situ hybridization on transplant kidney biopsies (n=8) for ubiquitin (UBC, positive control) and bacterial gene DapB (negative control) was performed. (A) A strong UBC (+) mRNA signal and a very low DapB (−) signal were observed. (B) The total UBC signal correlates strongly with the total cellular load in the biopsy (r = 0.86, p=0.02). Abbreviation: FFPE, formalin-fixed paraffin-embedded.
