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. 2020 Jul 8;6(7):e04331. doi: 10.1016/j.heliyon.2020.e04331

Figure 1.

Figure 1

LbNDT1 displays typical characteristics of the MCF. A. The topology model predicts the three tandem sequences (Repeats I–III) that establish six trans-membrane α helices (H1 – H6), and the N and C terminal regions toward the outer face of the membrane. B-E. A predictive model was obtained from the ROBETTA server, whose validation was completed by Ramachandran plots analysis with MolProbity. B. Top visualization of the six trans-membrane α helices (H1 – H6). C. Front visualization of the short α helices (h12, h34 and h56), located toward the inner face of the membrane. D. The N and C terminal regions are positioned towards the outer face of the membrane. E. Location of the Px[DE]xx[KR] (METS) (green) and [YF][DE]xx[KR] motifs (red). Images generated with UCSF Chimera (v 1.10.2).