Table 1.

Details of DNA lesions detected by constituent of enzymatic cocktail used and the termini of the strand breaks formed after the action of the respective enzymes.

Repair enzyme	DNA substrates for enzyme action	Termini of the strand breaks induced by the enzyme action
FpG	8-oxo-7,8- dihydroguanine 2,6-diamino-4-hydroxy-5-formamidopyrimidine	5′-phosphate 3′-phosphate
Endo III	5-hydroxy-5-methylhydantoin thymine glycol 5-hydroxy-6-hydrothymine uracil glycol 5-hydroxy-6-hydrouracil	3′-α, β-unsaturated aldehyde 5′-phosphate
Endo IV	AP site 3′-phosphate 3′-phosphoglycolate	dR5P OH
Endo VIII	urea thymine glycol 5-hydroxy-5-methylhydantoin uracil glycol 6-hydroxy-5, 6-dihydrothymine	5′-phosphate 3′-phosphate
APE1	AP site 3′-phosphate 3′-phosphoglycolate	dR5P OH