Table 3.
KEGG pathway analysis of DEGs.
| Pathway | ID | Count | p value | Genes |
|---|---|---|---|---|
| ECM-receptor interaction | hsa04512 | 5 | 4.03E-09 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B |
| Dilated cardiomyopathy (DCM) | hsa05414 | 5 | 6.84E-09 | ITGA1|ITGB3|PRKACA|ITGB1|ITGA2B |
| Human papillomavirus infection | hsa05165 | 6 | 8.06E-08 | THBS2|ITGB1|ITGB3|PRKACA|ITGA1|ITGA2B |
| Focal adhesion | hsa04510 | 5 | 2.31E-07 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | hsa05412 | 4 | 2.55E-07 | ITGA1|ITGB3|ITGB1|ITGA2B |
| Hypertrophic cardiomyopathy (HCM) | hsa05410 | 4 | 4.65E-07 | ITGA1|ITGB3|ITGB1|ITGA2B |
| Platelet activation | hsa04611 | 4 | 1.60E-06 | ITGB3|PRKACA|ITGB1|ITGA2B |
| Phagosome | hsa04145 | 4 | 3.52E-06 | ITGB3|THBS2|ITGB1|C3 |
| PI3K-Akt signaling pathway | hsa04151 | 5 | 3.71E-06 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B |
| Proteoglycans in cancer | hsa05205 | 4 | 1.08E-05 | ITGB3|PRKACA|ITGB1|PTPN6 |
| Regulation of actin cytoskeleton | hsa04810 | 4 | 1.32E-05 | ITGA1|ITGB3|ITGB1|ITGA2B |
| Leishmaniasis | hsa05140 | 3 | 1.89E-05 | ITGB1|PTPN6|C3 |
| Complement and coagulation cascades | hsa04610 | 3 | 2.29E-05 | PLAT|A2M |C3 |
| Hematopoietic cell lineage | hsa04640 | 3 | 4.15E-05 | ITGA1|ITGB3|ITGA2B |
| Fluid shear stress and atherosclerosis | hsa05418 | 3 | 0.000117572 | ITGB3|PLAT|ITGA2B |
| Cholesterol metabolism | hsa04979 | 2 | 0.00056172 | APOE|APOB |
| Thyroid hormone synthesis | hsa04918 | 2 | 0.001195438 | PRKACA|ALB |
| Pertussis | hsa05133 | 2 | 0.001258577 | ITGB1|C3 |
| Rap1 signaling pathway | hsa04015 | 3 | 0.00038722786 | ITGB3|ITGB1|ITGA2B |
| ECM-receptor interaction | hsa04512 | 5 | 4.03E-09 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B |
Abbreviation: KEGG: Kyoto Encyclopedia of Genes and Genomes; DEGs: differentially expressed genes.