Table 2.
Structures and natural forms of human TFF peptides at their predominant expression sites.
TFFs | Structures | Expression Sites | Natural Forms (Major/Minor) |
---|---|---|---|
TFF1 |
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Stomach |
TFF1mono TFF1-FCGBP TFF1-X (60 k) TFF1-GKN2 TFF1-TFF1 |
TFF2 |
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Stomach |
TFF2/MUC6 TFF2 |
TFF3 |
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Intestine, salivary glands |
TFF3-FCGBP TFF3-TFF3 TFF3mono |
Acidic residues flanking the C-terminal cysteines are shown in red. For TFF2, the N-linked carbohydrate moiety is depicted (yellow squares, GalNAc; blue squares, GlcNAc; green circles, Man; red triangles, Fuc). Major natural TFF forms are shown in bold.