Table 2.

Selected granule components of neutrophils/heterophils in different species.

	Human	Mouse	Rat	Horse	Cattle	Pig	Dog	Cat	Birds	Reptiles	Opossum	Fish	References
MPO 1	+	+	+	+	+	+	+	+	−	−	+	+/−	[1,66,99,101,102,106]
Lysozyme	+	+	+	+	−	+	+	−	+	+	(+)	(+)	[1,101,107]
AP 2	+	−	+	+	+	+	+	−	−	+/−	(0)	+/−	[1,101,102,108,109]
Lactoferrin	+	+	+	+	+	+	+	+	−	−	+	−	[104,110]
β-Glucuronidase	+	+	+	+	+	+	+	+	+	+	(0)	+/-	[94,101,105,111,112,113,114]
Defensin	+	−	+	−	+	(+)	(+)	(+)	+	+/−	(+)	(+)	[19,94,115,116,117,118,119,120,121,122,123]
MP 3	+	+	+	+	+	+	+	(0)	+	(0)	(0)	+	[94,124,125,126,127,128,129,130,131]
Elastase	+	+	+	+	+	+	+	+	+	(0)	+	+	[94,106,122,132,133,134,135,136,137,138]
BPI 4	+	+	+	(+)	+	+	(+)	(+)	(+)	(+)	(0)	+	[124,132,139,140,141,142,143,144,145,146]
Cathelicidin	+	+	+	+	+	+	+	+	+	+	(+)	(+)	[19,94,116,117,122,132,147,148,149]

¹ Myeloperoxidase, ² Alkaline phosphatase, ³ Metalloproteinases (gelatinase, leukolysin and/or collagenase), ⁴ Bactericidal permeability increasing protein, +/- present in some species, (+) sequence in genome but not stated if present in neutrophil, (0) no data found.