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Structure of the dZ-dP unnatural base pair and the corresponding hydrogen bonding interactions (left). Aptasensor for the electrochemical detection of HepG2 exosomes using nanotetrahedrons bearing the dZ-dP aptamers immobilized on a gold surface (right). Reprinted (adapted) with permission from ACS Nano 2017, 11, 4, 3943–3949. Copyright (2017) American Chemical Society.
